{"product_id":"abm208582","title":"Human Toll-like Receptor 5, TLR5 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ePattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed: 11323673, PubMed: 18490781). Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota (PubMed: 29934223). Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response (PubMed: 20855887, PubMed: 11489966). Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57661635297620,"sku":"ABM208582","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57661635330388,"sku":"ABM208583","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-3cd60cb92228eed77af192a086cef46a7037f6e6c85ff3531afd353273eeadf2.jpg?v=1792159165","url":"https:\/\/www.abmium.com\/es\/products\/abm208582","provider":"ABMIUM","version":"1.0","type":"link"}