{"product_id":"abm207940","title":"Sheep Interleukin-12 Subunit Beta, IL12B ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK\/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661638574420,"sku":"ABM207940","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661638607188,"sku":"ABM207941","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-70ee94dd2d606a79e5108ec594cee8abd0d73066ff2d0e6a2262ab6131926f38.jpg?v=1792159118","url":"https:\/\/www.abmium.com\/es\/products\/abm207940","provider":"ABMIUM","version":"1.0","type":"link"}