{"product_id":"abm207620","title":"Goat Integrin Beta2, ITG BETA 2 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eIntegrin ITGAL\/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL\/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM\/ITGB2 and ITGAX\/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX\/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM\/ITGB2 recognizes P1 and P2 Peptides of fibrinogen gamma chain. Integrin ITGAM\/ITGB2 is also a receptor for factor X. Integrin ITGAD\/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B\/PYK2-mediated activation. Integrin ITGAL\/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages. In association with alpha subunit ITGAM\/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57661263610196,"sku":"ABM207620","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57661263642964,"sku":"ABM207621","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-aecb005bae8eaeb62386e4a6000ac566f155b65b42856a63f44969280894e2a3.jpg?v=1792159096","url":"https:\/\/www.abmium.com\/es\/products\/abm207620","provider":"ABMIUM","version":"1.0","type":"link"}