{"product_id":"abm207500","title":"Human Interleukin 23, IL-23 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eInterleukin 23 (IL-23) is a member of the IL-12 cytokine family and composed of two subunits, IL-12 p40 and IL-23 p19. It is produced by antigen presenting cells and has been shown to promote the production and survival of a distinct lineage of T-cells called Th17 cells. A functional receptor for IL-23 (the IL-23 receptor) has been identified and is composed of IL-12Rβ1 and IL-23R. IL-23 is expressed chiefly by the macrophages and DCs. The IL-23R is found on memory T cells, NKT cells, macrophages, DCs, and naive T cells upon activation by TGF-β and IL-6. The main biological effects of IL-23 identified initially consist of stimulation of antigen presentation by DCs, T cell differentiation to Th17 cells, and production of interferon-γ (IFN-γ). IL-23 acts also as an end-stage effector cytokine through direct action on macrophages. This kit can be used to determine relative mass values for IL-23 p40.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57661146333524,"sku":"ABM207500","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57661146366292,"sku":"ABM207501","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1df67aed90294b149dc6bf387b6a47825ef60b46d5f1f4b4f701ff472ab62155.jpg?v=1792159087","url":"https:\/\/www.abmium.com\/es\/products\/abm207500","provider":"ABMIUM","version":"1.0","type":"link"}