{"product_id":"abm207272","title":"Human Visfatin, VISFATIN ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCatalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL\/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57660927115604,"sku":"ABM207272","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57660927148372,"sku":"ABM207273","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-47ccc9dde16cec604776946c779b7cfd8f53adfa30cf4180db6602b7768da2e2.jpg?v=1792159166","url":"https:\/\/www.abmium.com\/es\/products\/abm207272","provider":"ABMIUM","version":"1.0","type":"link"}