{"product_id":"abm207149","title":"Phospho-Catenin-Beta (S552) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCatenin beta 1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, catenin beta 1 binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.\u003c\/p\u003e\u003cp\u003e\u003cem\u003ePackaging image shown for reference. Select a size from the available options.\u003c\/em\u003e\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660810330452,"sku":"ABM207149","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660810363220,"sku":"ABM207150","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660810395988,"sku":"ABM207151","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f324e8429e766fa1531f7fd366db4d43d637484a38050b0923e08284f225198b.jpg?v=1792157294","url":"https:\/\/www.abmium.com\/es\/products\/abm207149","provider":"ABMIUM","version":"1.0","type":"link"}