{"product_id":"abm204921","title":"CSK Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCarboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk .Tissue specificity: Expressed in lung and macrophages.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661119332692,"sku":"ABM204921","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661119365460,"sku":"ABM204922","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1b474304766d6d17fdcf3f305ebf1952a6cda4d675e7246833054be17a9c1d77.jpg?v=1792159098","url":"https:\/\/www.abmium.com\/es\/products\/abm204921","provider":"ABMIUM","version":"1.0","type":"link"}