{"product_id":"abm203545","title":"CD124 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661561307476,"sku":"ABM203545","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661561340244,"sku":"ABM203546","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-51e848efc84d9168a663e50b81fc91b9d47a6667c03b27fab06a92d0cafd27b0.jpg?v=1792159131","url":"https:\/\/www.abmium.com\/es\/products\/abm203545","provider":"ABMIUM","version":"1.0","type":"link"}