{"product_id":"abm200879","title":"PKN1 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1\/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661150691668,"sku":"ABM200879","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661150724436,"sku":"ABM200880","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ac55c3e20ee4392172e476590b65451d32a18cc89bde01149968883908125398.jpg?v=1792158996","url":"https:\/\/www.abmium.com\/es\/products\/abm200879","provider":"ABMIUM","version":"1.0","type":"link"}