{"product_id":"abm200655","title":"TORC1 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eA chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11|19)(q21|p13) with MAML2. The fusion protein consists of the N-terminus of CRTC1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK\/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"50ul","offer_id":57660956475732,"sku":"ABM200655","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660956508500,"sku":"ABM200656","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-6811689a0b8ed0a2345d64a686e91dcec41f0b6ca3d777628b12e7e05a279d3e.jpg?v=1792158962","url":"https:\/\/www.abmium.com\/es\/products\/abm200655","provider":"ABMIUM","version":"1.0","type":"link"}