{"product_id":"abm199946","title":"JNK3 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"50ul","offer_id":57661162160468,"sku":"ABM199946","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661162193236,"sku":"ABM199947","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e3c9e262ca60d51508e2112a84ff19be2d8c1782e82454c95fe5d1576782b825.jpg?v=1792158963","url":"https:\/\/www.abmium.com\/es\/products\/abm199946","provider":"ABMIUM","version":"1.0","type":"link"}