{"product_id":"abm197861","title":"ZAP-70(Phospho Tyr319) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661043474772,"sku":"ABM197861","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661043507540,"sku":"ABM197862","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661043540308,"sku":"ABM197863","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-c07ebfb71744ffd1bb5645f7a3b195fecb502fa273ced52a55ff1a91fd120b47.jpg?v=1792158996","url":"https:\/\/www.abmium.com\/es\/products\/abm197861","provider":"ABMIUM","version":"1.0","type":"link"}