{"product_id":"abm191075","title":"PPIG Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCatalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA)-sensitive.,PPIases accelerate the folding of proteins.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the cyclophilin-type PPIase family.,Contains 1 PPIase cyclophilin-type domain.,subcellular location:Colocalizes with RNA splicing factors at nuclear speckles.,subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.,tissue specificity:Ubiquitous.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661344874836,"sku":"ABM191075","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661344907604,"sku":"ABM191076","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661344940372,"sku":"ABM191077","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/es\/products\/abm191075","provider":"ABMIUM","version":"1.0","type":"link"}