{"product_id":"abm188024","title":"Rac1\/cdc42(Phospho-Ser71) Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a small GTPase of the Rho-subfamily| which regulates signaling pathways that control diverse cellular functions including cell morphology| migration| endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42| and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP)| which subsequently activates Arp2\/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3| 4| 5| 7| 8 and 20.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660863906132,"sku":"ABM188024","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660863938900,"sku":"ABM188025","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660863971668,"sku":"ABM188026","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8f5b6dd6bd59a160432fdd4d006d97cd2f850978b673bc5fe8c46dfdb3f234b2.jpg?v=1792159027","url":"https:\/\/www.abmium.com\/es\/products\/abm188024","provider":"ABMIUM","version":"1.0","type":"link"}