{"product_id":"abm186115","title":"MUL1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe zinc finger domain is required for E3 ligase activity.,E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7\/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,Contains 1 RING-type zinc finger.,subcellular location:Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome.,subunit:Homooligomer. Interacts with MAP3K7\/TAK1.,tissue specificity:Widely expressed with highest levels in the heart, skeletal muscle, placenta, kidney and liver. Barely detectable in colon and thymus.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661278323028,"sku":"ABM186115","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661278355796,"sku":"ABM186116","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661278388564,"sku":"ABM186117","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-dd62502e62772a71c3e411e68969ad90f47d53cbb6674a81eaf75588e3eddb91.jpg?v=1792158949","url":"https:\/\/www.abmium.com\/es\/products\/abm186115","provider":"ABMIUM","version":"1.0","type":"link"}