{"product_id":"abm182164","title":"IBTK Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eBruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660955558228,"sku":"ABM182164","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660955590996,"sku":"ABM182165","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660955623764,"sku":"ABM182166","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/es\/products\/abm182164","provider":"ABMIUM","version":"1.0","type":"link"}