{"product_id":"abm181044","title":"HIF-1 beta Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660091695444,"sku":"ABM181044","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660091728212,"sku":"ABM181045","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660091760980,"sku":"ABM181046","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4010e8b2a135714fe8f20cd31249bf7918b295101674c85a99bdad0613f004b8.jpg?v=1792159013","url":"https:\/\/www.abmium.com\/es\/products\/abm181044","provider":"ABMIUM","version":"1.0","type":"link"}