{"product_id":"abm178693","title":"TNF-R2 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eTumor necrosis factor receptor superfamily member 1B encoded by TNFRSF1B is a member of the TNF-receptor superfamily. Tumor necrosis factor receptor superfamily member 1B and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660115222868,"sku":"ABM178693","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660115255636,"sku":"ABM178694","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660115288404,"sku":"ABM178695","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-90f1887087960e92a88e7f3cb02b6331ddd9100b712f620c8e86de21951eef68.jpg?v=1792158964","url":"https:\/\/www.abmium.com\/es\/products\/abm178693","provider":"ABMIUM","version":"1.0","type":"link"}