{"product_id":"abm178336","title":"TGFBeta3 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eTGFB3 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Transforming growth factor beta-3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659828994388,"sku":"ABM178336","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659829027156,"sku":"ABM178337","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659829059924,"sku":"ABM178338","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-cad41d1fb6b0426b604085f464c83c5c5addf58f0d2d9e23663992e3af6271b2.jpg?v=1792158863","url":"https:\/\/www.abmium.com\/es\/products\/abm178336","provider":"ABMIUM","version":"1.0","type":"link"}