{"product_id":"abm176650","title":"3HAO Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003e3-Hydroxyanthranilate 3|4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660322185556,"sku":"ABM176650","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660322218324,"sku":"ABM176651","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660322251092,"sku":"ABM176652","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-5194eaa9bc154da31b0776960a8c2264be614b0e569a591d1c53da5befdac01b.jpg?v=1792158897","url":"https:\/\/www.abmium.com\/es\/products\/abm176650","provider":"ABMIUM","version":"1.0","type":"link"}