{"product_id":"abm176365","title":"SH-PTP2 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eTyrosine-protein phosphatase non-receptor type 11 encoded by PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660128919892,"sku":"ABM176365","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660128952660,"sku":"ABM176366","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660128985428,"sku":"ABM176367","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-975d210720dc0f22d5848bed59aa23d497adc9eecfacf940107b0db7551d1a8c.jpg?v=1792158861","url":"https:\/\/www.abmium.com\/es\/products\/abm176365","provider":"ABMIUM","version":"1.0","type":"link"}