{"product_id":"abm172231","title":"Caspase 2 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ealternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.|Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.|PTM:The mature protease can process its own propeptide| but not that of other caspases.|Belongs to the peptidase C14A family.|Contains 1 CARD domain.|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.|tissue specificity:Expressed at higher levels in the embryonic lung| liver and kidney than in the heart and brain. In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle.|\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57659742912852,"sku":"ABM172231","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659742945620,"sku":"ABM172232","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57659742978388,"sku":"ABM172233","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/es\/products\/abm172231","provider":"ABMIUM","version":"1.0","type":"link"}