{"product_id":"abm171847","title":"p300 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eEP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660475834708,"sku":"ABM171847","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660475867476,"sku":"ABM171848","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660475900244,"sku":"ABM171849","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-80da93961ad36181c5fd8cf2f69b743db7893da93e92ebc791c93c9d4bdc793a.jpg?v=1792158900","url":"https:\/\/www.abmium.com\/es\/products\/abm171847","provider":"ABMIUM","version":"1.0","type":"link"}