{"product_id":"abm171319","title":"HDAC3(Phospho Ser424) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660000108884,"sku":"ABM171319","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660000141652,"sku":"ABM171320","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660000174420,"sku":"ABM171321","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-3a96839e90f37349325b67b22218acb4044a1bf9077783461ec95f4d546f5e3d.jpg?v=1792158860","url":"https:\/\/www.abmium.com\/es\/products\/abm171319","provider":"ABMIUM","version":"1.0","type":"link"}