{"product_id":"abm169135","title":"APOB Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms| apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single| very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA-\u0026gt;UAA)| resulting in the creation of a stop codon| and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia| normotriglyceridemic hypobetalipoproteinemia| and hypercholesterolemia due to ligand-defective apoB| diseases affecting plasma cholesterol and apoB levels.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660134555988,"sku":"ABM169135","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660134588756,"sku":"ABM169136","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660134621524,"sku":"ABM169137","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/es\/products\/abm169135","provider":"ABMIUM","version":"1.0","type":"link"}