{"product_id":"abm163447","title":"HDAC5 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase\/acuc\/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for HDAC5.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660483600724,"sku":"ABM163447","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660483633492,"sku":"ABM163448","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660483666260,"sku":"ABM163449","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-23e134f8e4de58dfdc5db6c577a7ff4513ccccff3993d1f72fc951866ceaf3e3.jpg?v=1792157314","url":"https:\/\/www.abmium.com\/es\/products\/abm163447","provider":"ABMIUM","version":"1.0","type":"link"}