{"product_id":"abm161914","title":"Gab 2\/4 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and\/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]ADRB2 (Adrenoceptor Beta 2) is a Protein Coding gene. Diseases associated with ADRB2 include obesity and asthma. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. GO annotations related to this gene include G-protein coupled receptor activity and enzyme binding. An important paralog of this gene is TAAR9. eta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. he adrenergic beta2 receptor (beta2-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C, beta1 and beta3. They are located primarily in the CNS, heart, kidney and muscle.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660161622356,"sku":"ABM161914","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660161655124,"sku":"ABM161915","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660161687892,"sku":"ABM161916","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-5742df7b66af7090530f853b50bbe38d33864ddfa7dba19f6840bdfc25ac7c51.jpg?v=1792157377","url":"https:\/\/www.abmium.com\/es\/products\/abm161914","provider":"ABMIUM","version":"1.0","type":"link"}