{"product_id":"abm161062","title":"FADD Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eProtein FADD encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, protein FADD can be recruited by TNFRSF6\/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10\/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of protein FADD with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660518728020,"sku":"ABM161062","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660518760788,"sku":"ABM161063","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660518793556,"sku":"ABM161064","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4a50a3210ad8bfce9b5ddcf4332b3d0cbf0582b804d8e5f9c08c7402d7894507.jpg?v=1792157388","url":"https:\/\/www.abmium.com\/es\/products\/abm161062","provider":"ABMIUM","version":"1.0","type":"link"}