{"product_id":"abm159670","title":"DNA pol iota Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ePOLI (Polymerase (DNA) Iota) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Fanconi anemia pathway. GO annotations related to this gene include damaged DNA binding and DNA-directed DNA polymerase activity. An important paralog of this gene is POLH. rror-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5-deoxyribose phosphate at abasic sites, but may not have lyase activity.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660150120788,"sku":"ABM159670","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660150153556,"sku":"ABM159671","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660150186324,"sku":"ABM159672","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-fac69ebf222ca2fef8b6cbc61010303fd130e3a607d401446dc03e0b958c04ad.jpg?v=1792157340","url":"https:\/\/www.abmium.com\/es\/products\/abm159670","provider":"ABMIUM","version":"1.0","type":"link"}