{"product_id":"abm157909","title":"COL25A1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for COL25A1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659800191316,"sku":"ABM157909","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659800224084,"sku":"ABM157910","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659800256852,"sku":"ABM157911","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7be4095575a093bd67d2d412853677c61607aedf407321394cb45d75c4f774f1.jpg?v=1792157323","url":"https:\/\/www.abmium.com\/es\/products\/abm157909","provider":"ABMIUM","version":"1.0","type":"link"}