{"product_id":"abm155808","title":"CD160 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1. and 1. kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660060598612,"sku":"ABM155808","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660060631380,"sku":"ABM155809","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660060664148,"sku":"ABM155810","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-a56848e6d7ae29dbc7f5ea8d6a614db77f6dc75c50c951e21fea309a876afd45.jpg?v=1792157356","url":"https:\/\/www.abmium.com\/es\/products\/abm155808","provider":"ABMIUM","version":"1.0","type":"link"}