{"product_id":"tribio-tpca-1-ikk2-inhibitor-selective","title":"TPCA-1, IKK2 inhibitor (selective)","description":"\u003cp\u003eSelective inhibitor of IκB kinase 2 (IKK2) (IC50 = 17.9 nM). Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation. Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses IL1β-induced proliferation, migration, and invasion of HeLa cells. Continuous exposure to TPCA-1 promotes expansion of hematopoietic stem\/progenitor cells (HSPCs) via improved glycolysis and limited ROS production\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411083829588,"sku":"ABM148871-1","price":327.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57411083862356,"sku":"ABM148871-2","price":114.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI5571.png?v=1791105167","url":"https:\/\/www.abmium.com\/de\/products\/tribio-tpca-1-ikk2-inhibitor-selective","provider":"ABMIUM","version":"1.0","type":"link"}