{"product_id":"tribio-smi-4a-pim1-inhibitor","title":"SMI-4a, PIM1 inhibitor","description":"\u003cp\u003eA selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases. Induces cell cycle arrest in leukemia and prostate cancer cells. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia\/lymphoma (pre-T-LBL\/T-ALL) being highly sensitive. A useful tool for exploring the involvement of Pim in cellular signaling. Cell permeable\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411076817236,"sku":"ABM148754-1","price":278.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57411076850004,"sku":"ABM148754-2","price":82.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1359.png?v=1791105151","url":"https:\/\/www.abmium.com\/de\/products\/tribio-smi-4a-pim1-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}