{"product_id":"tribio-skf-96365-trpc-channel-blocker","title":"SKF-96365, TRPC channel blocker","description":"\u003cp\u003eAn inhibitor of receptor-mediated calcium entry (RMCE) with IC50‘s of 8.5 μM for ADP stimulated platelets and 11.7 μM for thrombin stimulated platelets. Also inhibits Voltage-gated Ca 2+ but not ATP-gated Ca 2+ entry. It has also been shown to block transient receptor potential canonical type (TRPC) channels, high-voltage-activated (HVA) L-type channels, K channels, sarcoplasmic reticulum Ca-ATPase and voltage-gated sodium channels. SKF-96365 is a potent blocker of LVA T-type Ca channels, in particular Ca(V)3.1 (IC50 = 0.56 μM)\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411069935956,"sku":"ABM148746-1","price":425.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57411069968724,"sku":"ABM148746-2","price":106.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1068.png?v=1791105007","url":"https:\/\/www.abmium.com\/de\/products\/tribio-skf-96365-trpc-channel-blocker","provider":"ABMIUM","version":"1.0","type":"link"}