{"product_id":"tribio-pd-150606-calpain-inhibitor","title":"PD-150606, Calpain inhibitor","description":"\u003cp\u003eA selective, cell-permeable non-peptide calpain inhibitor (Ki for μ- and m-calpains = 0.21 and 0.37 μM respectively). Acts at the calcium binding site of calpain rather than the substrate-binding site. Inhibits calpain activity in two intact cell systems. Attenuates hypoxic\/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices. Displays cytoprotective effects in oxidant- and calcium ionophore-induced cell death. Some protective effects may be due to inhibition of MMP activity\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410961899860,"sku":"ABM147514-1","price":451.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410961932628,"sku":"ABM147514-2","price":113.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1515.png?v=1791104187","url":"https:\/\/www.abmium.com\/de\/products\/tribio-pd-150606-calpain-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}