{"product_id":"tribio-nsc-405020-mt1-mmp-inhibitor","title":"NSC-405020, MT1-MMP inhibitor","description":"\u003cp\u003eMembrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 \u0026gt; 100 μM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model. Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410936799572,"sku":"ABM147455-1","price":393.0,"currency_code":"USD","in_stock":true},{"title":"5 MG","offer_id":57410936832340,"sku":"ABM147455-2","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1462.png?v=1791103989","url":"https:\/\/www.abmium.com\/de\/products\/tribio-nsc-405020-mt1-mmp-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}