{"product_id":"tribio-mls-544460-eya2-phosphatase-inhibitor","title":"MLS-544460, Eya2 phosphatase inhibitor","description":"\u003cp\u003eMLS-544460 is an allosteric inhibitor of the Eya2 tyrosine phosphatase (IC 50 =4.1 µM) which is ineffective against other tyrosine phosphatases including Eya3 and PTP1B. Treatment of patient-derived glioma stem cells induced loss of bipolar spindle formation along with G2\/M cell cycle arrest. GSC proliferation was inhibited at concentrations 4 to 10-fold lower than normal brain cells. Treatment of Axolotls following amputation impairs limb regeneration indicating a role for Eya2 in vertebrate regeneration\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410941714772,"sku":"ABM147372-1","price":480.0,"currency_code":"USD","in_stock":true},{"title":"5 MG","offer_id":57410941747540,"sku":"ABM147372-2","price":131.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI5332.png?v=1791104000","url":"https:\/\/www.abmium.com\/de\/products\/tribio-mls-544460-eya2-phosphatase-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}