{"product_id":"tribio-mf-438-scd1-inhibitor","title":"MF-438, SCD1 inhibitor","description":"\u003cp\u003eMF-438 is a potent inhibitor of stearoyl-CoA desaturase 1 (SCD1) – IC50 = 2.3 nM. MF-438 was potent in an in vivo mouse liver PD assay (ED50 between 1 and mg\/kg). Cancer initiating cells (CSC-like) were shown to much more sensitive to MF-438 inhibition of SCD1 than progenitor and terminally differentiated cancer cells in a lung cancer model. MF-438 showed good oral bioavailability and metabolic stability making it an excellent tool for studying the effects of SCD1 in various disease models\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410943942996,"sku":"ABM147326-1","price":409.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410943975764,"sku":"ABM147326-2","price":98.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4558.png?v=1791104005","url":"https:\/\/www.abmium.com\/de\/products\/tribio-mf-438-scd1-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}