{"product_id":"tribio-knk437-hsp70-inhibitor","title":"KNK437, HSP70 inhibitor","description":"\u003cp\u003eInhibits constitutive and inducible HSP70 expression in non-stressed and heat-stressed cancer cells. Blocks geldanamycin-induced induction of HSP70 and inhibition of TGFß signaling. Inhibits leukocyte integrin α4ß7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1), suggesting that HSP70 is essential for ß7 integrin signalling. Suppresses morphine analgesic tolerance in a rodent model (100 mg\/Kg)\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410919530836,"sku":"ABM147238-1","price":294.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410919563604,"sku":"ABM147238-2","price":98.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI5561.png?v=1791103638","url":"https:\/\/www.abmium.com\/de\/products\/tribio-knk437-hsp70-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}