{"product_id":"tribio-jnj-63533054-gpr139-agonist-suppresses-morphine-intake","title":"JNJ-63533054, GPR139 agonist, suppresses morphine intake","description":"\u003cp\u003eJNJ-63533054 is a potent and selective brain-penetrant GPR139 agonist (EC50=16 nM) an orphan G-protein-coupled receptor expressed in the CNS. Tritium-labeled JNJ-63533054 binds to cell membranes expressing GPR139 and can be displaced by putative endogenous ligands. Decreases compulsive-like alcohol drinking and hyperalgesia in alcohol-dependent rodents. Suppresses morphine intake in a mouse self-administration model\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410911633748,"sku":"ABM147214-1","price":425.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410911666516,"sku":"ABM147214-2","price":114.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI3880.png?v=1791103620","url":"https:\/\/www.abmium.com\/de\/products\/tribio-jnj-63533054-gpr139-agonist-suppresses-morphine-intake","provider":"ABMIUM","version":"1.0","type":"link"}