{"product_id":"tribio-bo-264-tacc3-inhibitor","title":"BO-264, TACC3 inhibitor","description":"\u003cp\u003eBO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity. TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410870116692,"sku":"ABM146734-1","price":392.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410870149460,"sku":"ABM146734-2","price":106.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4685.png?v=1791103245","url":"https:\/\/www.abmium.com\/de\/products\/tribio-bo-264-tacc3-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}