{"product_id":"reed-biotech-tirap-phospho-tyr86-polyclonal-antibody-ra30511","title":"TIRAP (phospho Tyr86) Polyclonal Antibody","description":"\u003cp\u003eTIR domain containing adaptor protein(TIRAP) Homo sapiens The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250450145620,"sku":"ABM5034905-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250450178388,"sku":"ABM5034905-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_114b63ab-d181-4607-b1fc-f325a3e6d4e6.webp?v=1790235367","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-tirap-phospho-tyr86-polyclonal-antibody-ra30511","provider":"ABMIUM","version":"1.0","type":"link"}