{"product_id":"reed-biotech-skp2-p45-monoclonal-antibody-ra11985","title":"Skp2 p45 Monoclonal Antibody","description":"\u003cp\u003eS-phase kinase associated protein 2(SKP2) Homo sapiens This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and int\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249698775380,"sku":"ABM5042815-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249698808148,"sku":"ABM5042815-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_11ad85fb-1757-4abd-896b-5210631701e7.webp?v=1790235188","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-skp2-p45-monoclonal-antibody-ra11985","provider":"ABMIUM","version":"1.0","type":"link"}