{"product_id":"reed-biotech-pkd1-polyclonal-antibody-ra34116","title":"PKD1 Polyclonal Antibody","description":"\u003cp\u003epolycystin 1, transient receptor potential channel interacting(PKD1) Homo sapiens This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell\/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on c\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249622557012,"sku":"ABM5038510-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249622589780,"sku":"ABM5038510-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_c36f5ed6-f425-486f-bde1-5fa746ea485d.webp?v=1790234909","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-pkd1-polyclonal-antibody-ra34116","provider":"ABMIUM","version":"1.0","type":"link"}