{"product_id":"reed-biotech-p3c2b-polyclonal-antibody-ra33948","title":"P3C2B Polyclonal Antibody","description":"\u003cp\u003ephosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta(PIK3C2B) Homo sapiens The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250299740500,"sku":"ABM5038342-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250299773268,"sku":"ABM5038342-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_3969af7f-84e8-4aed-8922-59b1c1b55239.webp?v=1790234789","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-p3c2b-polyclonal-antibody-ra33948","provider":"ABMIUM","version":"1.0","type":"link"}