{"product_id":"reed-biotech-p21-acetyl-lys154-rabbit-polyclonal-antibody-ra28315","title":"p21 (Acetyl Lys154) Rabbit Polyclonal Antibody","description":"\u003cp\u003efunction:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.,induction:By p53, mezerein (antileukemic compound) and interferon beta.,PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250090352980,"sku":"ABM5032709-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250090385748,"sku":"ABM5032709-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_c82fa22f-ebb8-43bc-939f-0b0cc42c8bc1.webp?v=1790234781","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-p21-acetyl-lys154-rabbit-polyclonal-antibody-ra28315","provider":"ABMIUM","version":"1.0","type":"link"}