{"product_id":"reed-biotech-nprl2-polyclonal-antibody-ra27927","title":"NPRL2 Polyclonal Antibody","description":"\u003cp\u003efunction:Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.,similarity:Belongs to the NPR2 family.,subunit:Interacts with PDPK1.,tissue specificity:Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251046392148,"sku":"ABM5032321-1","price":137.0,"currency_code":"USD","in_stock":true},{"title":"100 µL","offer_id":57251046424916,"sku":"ABM5032321-2","price":184.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_47bda67f-75c8-4e7f-94a1-94403b9c6f99.webp?v=1790234654","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-nprl2-polyclonal-antibody-ra27927","provider":"ABMIUM","version":"1.0","type":"link"}