{"product_id":"reed-biotech-kir3-1-polyclonal-antibody-ra26660","title":"KIR3.1 Polyclonal Antibody","description":"\u003cp\u003epotassium voltage-gated channel subfamily J member 3(KCNJ3) Homo sapiens Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down\u0026amp;apos;s syndrome, at\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250396340564,"sku":"ABM5031054-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250396373332,"sku":"ABM5031054-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-kir3-1-polyclonal-antibody-ra26660","provider":"ABMIUM","version":"1.0","type":"link"}