{"product_id":"reed-biotech-jnk1-2-3-polyclonal-antibody-ra20820","title":"JNK1\/2\/3 Polyclonal Antibody","description":"\u003cp\u003emitogen-activated protein kinase 8(MAPK8) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57248162677076,"sku":"ABM5025214-1","price":137.0,"currency_code":"USD","in_stock":true},{"title":"100 µL","offer_id":57248162709844,"sku":"ABM5025214-2","price":184.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-jnk1-2-3-polyclonal-antibody-ra20820","provider":"ABMIUM","version":"1.0","type":"link"}