{"product_id":"reed-biotech-ikaros-c-term-mouse-monoclonal-antibody-ra10541","title":"Ikaros (C-term) Mouse Monoclonal Antibody","description":"\u003cp\u003eIKAROS family zinc finger 1(IKZF1) Homo sapiens This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249789608276,"sku":"ABM5041371-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249789641044,"sku":"ABM5041371-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-ikaros-c-term-mouse-monoclonal-antibody-ra10541","provider":"ABMIUM","version":"1.0","type":"link"}